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Souris Complement (Lyophilized) With Diluent

Hôte: Souris Normal Complement
Rockland
N° du produit ABIN925150
N° du produit (Fournisseur): c201-0005

Aperçu rapide pour Souris Complement (Lyophilized) With Diluent (ABIN925150)

Hôte

Souris

Lysate Type

Normal

Protein Source

Complement
  • N° du produit (Fournisseur)

    c201-0005

    Fournisseur

    Rockland

    Specificité

    The mouse complement system consists of a number of small proteins found in the blood, generally synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex. Over 25 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. They account for about 5% of the globulin fraction of blood serum.

    Attributs du produit

    Strain: Mouse - Mixed
    Sex: Male

    Stérilité

    Non-sterile

    Ingrédients

    Mouse Complement (Lyophilized) With Diluent
  • Indications d'application

    pH: normal Immunoelectrophoresis: normal Hemoglobin: normal IgG Concentration: normal Immunoelectrophoresis: normal

    Commentaires

    The complement system helps or “complements” the ability of antibodies and phagocytic cells to clear pathogens from an organism. Complement is part of the innate immune system that is not adaptable and does not change over the course of an individual's lifetime. Complement can be recruited and brought into action by the adaptive immune system. The following are basic functions of complement: 1. Opsonisation - enhancing phagocytosis of antigens 2. Chemotaxis - attracting macrophages and neutrophils 3. Cell Lysis - rupturing membranes of foreign cells 4. Clumping of antigen-bearing agents

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 5.0 mL

    Concentration

    82 mg/mL

    Conseil sur la manipulation

    Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. COMPLEMENT IS A TEMPERATURE SENSITIVE PRODUCT. IMPROPER STORAGE WILL INACTIVATE COMPLEMENT ACTIVITY.

    Stock

    4 °C

    Date de péremption

    12 months
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